Peripheral Neuropathy,

also called Nerve Pain or Neuropathic Pain (NP) is characterised by feelings of numbness, uncomfortable tingling, burning or coldness, and/or itchiness mainly in the hands and feet.

There are many things that can cause NP, including metabolic issues (diabetes is the most common cause), physical injuries, infections, autoimmune issues (i.e. multiple sclerosis) and neurological issues.

Current treatments focus on relieving pain through drug therapies, but these have limited efficacy and dose-limiting toxic effects.

Hyperbaric oxygen therapy (HBOT) may relieve symptoms of peripheral neuropathy (NP) by reducing inflammatory damage and stimulating new nerve and blood vessel growth.

Nerve damage in NP causes inflammation in the surrounding neurons and non-neural cells.

HBOT can combat the damage that such inflammation causes by significantly reducing pro- inflammatory markers, increasing oxygen supply, and stimulating the growth of new blood vessels.

Additionally, HBOT can stimulate the growth of new nerve cells by increasing the availability and proliferation of stem cells, positively effecting vascular and nerve tissue responses.

When combined, these effects provide relief and potential recovery from NP.

Hyperbaric oxygen therapy (HBOT) may relieve symptoms of peripheral neuropathy (NP) by reducing inflammatory damage and stimulating new nerve and blood vessel growth.

Nerve damage in NP causes inflammation in the surrounding neurons and non-neural cells.

HBOT can combat the damage that such inflammation causes by significantly reducing pro- inflammatory markers, increasing oxygen supply, and stimulating the growth of new blood vessels.

Additionally, HBOT can stimulate the growth of new nerve cells by increasing the availability and proliferation of stem cells, positively effecting vascular and nerve tissue responses.

When combined, these effects provide relief and potential recovery from neuropathy pain.

 Ding Y, Yao P, Hong T, Han Z, Zhao B, Chen W. The NO-cGMP-PKG signal transduction pathway is involved in the analgesic effect of early hyperbaric oxygen treatment of neuropathic pain. J Headache Pain. 2017;18(1):51.

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